About the Center

Innovation Fund Denmark has granted 24 million DKK to BrainStem – Stem Cell Center of Excellence in Neurology - which will do research in neurodegenerative diseases over a 6 year period - from 2015 until 2020. The coordinator of the project is Professor Poul Hyttel, University of Copenhagen with the primary locations of activity being University of Copenhagen, Lund University, Danish Dementia Research Centre, Rigshospitalet University of Copenhagen, University of Southern Denmark, Aarhus University, Bioneer, Lundbeck A/S, Innovative Concepts in Drug Development.

Advanced stem cell technologies will be used to re-program skin cells from patients with Alzheimer’s and Parkinson’s diseases to diseased neurons. The researchers will thus have a close look at the molecular mechanisms behind neudegenerative diseases. The hope is that these diseased cells can be used to develop better diagnostics and to test new drugs.

Partners

  • The Group for Stem Cells and Embryology, University of Copenhagen (Poul Hyttel)
  • The Bioinformatics Group, Center for non-coding RNA in Technology and Health (RTH), University of Copenhagen (Jan Gorodkin)
  • The Group for Bioethics, Department of Food and Resource Economics, University of Copenhagen (Peter Sandøe)
  • The Danish Research Institute of Translational Neuroscience (DANDRITE), Stem Cell Group, Aarhus University (Mark Denham)
  • The Group for Genome Editing and Regenerative Medicine, Department of Biomedicine, Aarhus University (Yonglun Luo)
  • The Group for Stem Cells and Developmental Neurobiology, University of Southern Denmark (Morten Meyer)
  • The Group of Developmental Neurobiology, Wallenberg Neuroscience Center, Lund University (Malin Parmar)
  • The Stem Cell Laboratory for CNS disease Modelling, Wallenberg Neuroscience Center, Lund University (Laurent Roybon)
  • The Experimental Dementia Research Unit, Wallenberg Neuroscience Center, Lund University (Gunnar K. Gouras)
  • The Danish Dementia Research Centre (DDRC), Rigshospitalet, University of Copenhagen (Gunhild Waldemar)
  • H. Lundbeck (Karina Fog)
  • Bioneer A/S (Christian Clausen)
  • Innovative Concepts in Drug Development (ICDD), France (Nathalie Compagnone) 

BrainStem Steering Group

BrainStem will be managed by Professor Poul Hyttel, who has a long-standing experience in management of large research activities supported by the Danish Research Councils, the Danish National Advanced Technology Foundation (HTF), and the EU. The members of the Steering Group are:

  • Poul Hyttel, University of Copenhagen
  • Jan Gorodkin, University of Copenhagen
  • Kristine Freude, University of Copenhagen
  • Karina Garnier Christensen, University of Copenhagen
  • Peter Sandøe, University of Copenhagen
  • Gunhild Waldemar, The Danish Dementia Research Centre (DDRC), Rigshospitalet, University of Copenhagen 
  • Laurent Roybon, Lund University
  • Agnete Kirkeby, Lund University
  • Gunnar Gouras, Lund University
  • Morten Meyer, University of Southern Denmark
  • Mark Denham, Aarhus University
  • Yonglun Luo, Aarhus University
  • Karina Fog, H. Lundbeck
  • Christian Clausen, Bioneer A/S
  • Nathalie Compagnone, ICDD, France

Two internationally recognized experts in the field have agreed to serve as external members in the Steering Group:

  • Jari Koistinaho, University of Eastern Finland
  • Frank Edenhofer, Julius-Maximilians-University Würzburg, Germany