NeuroStem
BrainStem Summer Symposium, Aug 28-29, 2017
The second annual BrainStem Symposium will take place in Aarhus on Aug 28-29, 2017. The lectures are open to everybody. Lunch is available for the participants who signed up for the symposium only.
Programme:
DAY 1: AUGUST 28, 2017
09.30 Arrival and coffee
10.00-10.20 Welcome and overview (Poul Hyttel)
10.20-11.05 Keynote Lecture by Poul Henning Jensen, Dandrite, AU. Title: Parkinson’s disease and synucleinopathies – what to model, why and how?
Session 1 Neural development and differentiation (session chair: Stefan Seemann)
11.05-11.15 Overview of activities in relation to BrainStem (Agnete Kirkeby)
11.15-11.30 Presenter: Pedro Rifes (Kirkeby’s group). Title: Studying human early neural patterning using a microfluidic-controlled hESC-culturing device
11.30-11.45 Presenter: Yong Liu (Hall’s group). Title: Anatomical and molecular insight into the developing entorhinal cortex in a large mammalian species, the pig
Session 2 Generation of induced pluripotent stem cells and gene editing (session chair: Jonathan Wardman)
11.45-11.55 Overview of activities in relation to BrainStem (Bjørn Holst)
11.55-12.10 Patient specific lines overview (Kristine Freude)
12.10-12.25 Presenter: Henriette Frederiksen (Freude’s group). Title: Generation of induced mutations for AD
12.25-13.15 Lunch (1st floor conference room)
Session 3 iPSC-derived modeling of neurodegeneration (PD focus) (session chair: Katarina Willén)
13.20-13.30 Overview of activities in relation to BrainStem (Laurent Roybon)
13.30-13.45 Presenter: Kaspar Russ (Roybon’s group). Title: Glial pathology in synucleinopathies
13.45-14.00 Presenter: Muwan Chen (Denham’s group). Title: Investigating the role of Alpha-Synuclein in GBA1 iPSC-derived neurons
14:00-14:15 Presenters: Helle Bogetofte Barnkob & Justyna Okarmus (Meyer’s group). Title: Comprehensive proteomic and metabolomic characterisation of isogenic PARK2 iPSC-derived neurons
14:15- 14:35 Coffee Break
Session 4 iPSC-derived modeling of neurodegeneration (AD and FTD focus (session chair: Justyna Okarmus)
14:40 – 14:50 Overview of activities in relation to BrainStem (Kristine Freude)
14.50 – 15:05 Presenter: Katarina Willén (Goura’s group). Title: Endosome phenotypes in Alzheimer’s neurons
15:05 – 15:20 Presenter: Benjamin Schmid (Clausen’s group). Title: Celluar inducible MAPT models
15:20 – 15:35 Presenter: Tina Stummann (Fog’s group). Title: Establishing Tau and Alpha-synuclein seeding models in iPSC neurons
15:35 – 16:00 Coffee Break
Session 5 Diagnostic and clinical aspects of neurodegeneration. (session chair: Camilla Højlund Knudsen)
16:05-16.15 Overview of activities in relation to BrainStem (Steen G Hasselbalch)
16.15-16.30 Presenter: Jonathan Wardman (Nielsen’s group). Title: Pathophysiological mechanism of Spinocerebellar Ataxia Type 2: Role of oxidative stress and proteostasis
19.00 BrainStem dinner at Restaurant Flammen, Toldbodgade 6, 8000 Aarhus C
DAY 2: August 29, 2017
08.30-11.00 Steering Group meeting (SG members only)
08.30-11.00 Master Student, PhD and postdoc only session – Scientific Speed Dating. (See the attached programme for the event for more details)
Session 6 Ethics (session chair: Mette Habekost)
11.05-11.15 Overview of activities in relation to BrainStem (Peter Sandøe)
11.15-11.30 Presenter: Peter Sandøe. Title: Ethical aspects of informed consent models
Session 7 Bioethics workshop
11.30 – 12.30 Workshop activities (Peter Sandøe and Mickey Gjerris)
12.30-13.30 Lunch
Session 8 RNA-mediated mechanisms and bioinformatics in neurodegeneation (session chair: Kristine Freude)
13.35 – 13.45 Overview of activities in relation to BrainStem (Jan Gorodkin)
13.45 – 14.00 Next Generation Sequencing in BGI (Yonglun Luo)
14.00 – 14.15 Presenter: Christian Anthon (Gorodkin’s group). Title: Update on APOE cell line RNAseq
14.15-14.20 Symposium closing remarks (Poul Hyttel)